2021 Porsche Panamera 4S specs & fuel economy
The 2021 Porsche Panamera 4S is rated 20 MPG combined by the EPA (18 city, 24 highway). That is 17% below the 24.1 MPG average across the 85 EPA configurations in the 2021 Large Cars class, placing it in the 41st percentile of its class. At 12,000 miles at $3.50/US gallon it costs about $2,100 a year to run.
EPA data snapshot imported 2026-09-06 · United States · US gallons
The 2021 Porsche Panamera 4S has 1 EPA-listed configuration in our 2026-09-06 data snapshot. Listed transmissions: Automatic (AM-S8). Compare the engine, drive type and fuel ratings below before matching an individual car by VIN.
How the 2021 Porsche Panamera 4S compares in its class
EPA publishes each configuration on its own. Ranking one against every configuration EPA rated in the same class and model year is our calculation from the 2026-09-06 snapshot, not an EPA figure.
- Combined rating
- 20 MPG
- 2021 Large Cars average
- 24.1 MPG
- Difference
- 17% below average
- Rank in class
- 41th percentile of 85 configurations
- Reference annual energy cost
- $2,100 · 12,000 miles at $3.50/US gallon
The class average covers every 2021 configuration EPA rated in the Large Cars class, compared in MPG only, so electric and liquid-fuel ratings are never mixed. The reference cost is a fixed assumption for comparison; the calculator below takes your own mileage and prices.
Engine, transmission and fuel economy
The single 2021 Panamera 4S configuration EPA rated, with a link to its source record. Combined primary-fuel ratings: 20 MPG. Missing values remain “Not reported.”
| Engine / transmission / drive | Primary fuel | City | Highway | Combined | Source |
|---|---|---|---|---|---|
| 2.9L 6-cyl · Automatic (AM-S8) · All-Wheel DriveEPA engine descriptor: SIDI | Premium Gasoline | 18 MPG | 24 MPG | 20 MPG | EPA #43731 |
Other 2021 Porsche Panamera versions
EPA lists these versions separately. The figures above apply to the listing named “Panamera 4S”; they are not a specification for every Panamera trim.
What would it cost you to run?
Enter your own mileage and prices — these are assumptions, not live pump prices.
| Configuration | Annual cost | Calculation basis |
|---|---|---|
| 2.9L 6-cyl · Automatic (AM-S8) · All-Wheel DriveEPA #43731 | $2,100 | Premium Gasoline operation |
Miles ÷ combined MPG × price per gallon; electric versions use miles ÷ 100 × kWh/100 miles × price per kWh. Plug-in hybrids show gasoline operation only. Maintenance, insurance and depreciation are excluded.
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See what the paid report includes →Use these specs to check a 2021 Panamera 4S listing
- Confirm the seller’s car is a 2021 Porsche Panamera 4S with the Automatic (AM-S8).
- Check that it takes Premium Gasoline on the vehicle’s own fuel label.
- Run the VIN for identity, title and reported history — none of which is in this EPA data.
- Check open recalls on the NHTSA lookup and have the car inspected.
Compare nearby model years
These links match the EPA model name. They do not establish that parts or equipment are interchangeable between years.
Sources reviewed
Open the underlying public source and verify that its scope matches the question you are asking.
Frequently asked questions
What is the gas mileage of the 2021 Porsche Panamera 4S?
The 2021 Porsche Panamera 4S is rated 20 MPG combined by the EPA (18 city, 24 highway). That is 17% below the 24.1 MPG average across the 85 EPA configurations in the 2021 Large Cars class, placing it in the 41st percentile of its class. At 12,000 miles at $3.50/US gallon it costs about $2,100 a year to run.
What transmission does the 2021 Porsche Panamera 4S have?
EPA records list Automatic (AM-S8) across the 1 rated configuration of the 2021 Porsche Panamera 4S. These are model-level configurations. Match the individual car’s VIN and factory build information before identifying a replacement transmission.
What fuel does the 2021 Porsche Panamera 4S use?
The 2021 Porsche Panamera 4S is listed with Premium Gasoline. Match the particular configuration and follow the vehicle’s fuel label and owner’s manual.
How much does the 2021 Porsche Panamera 4S cost to run per year?
About $2,100 in fuel or energy at 12,000 miles at $3.50/US gallon, using the 20 MPG combined EPA rating. That excludes maintenance, insurance, depreciation and charging-session fees. Enter your own mileage and prices in the calculator on this page for a figure that matches your driving.
Are these the exact specifications of my Panamera 4S?
These are the 1 EPA model-year configuration recorded for the 2021 Porsche Panamera 4S, not a decode of an individual VIN or a complete trim catalogue. Confirm identity, installed equipment and service requirements with the car’s VIN and manufacturer records.
Will I achieve the listed fuel economy?
EPA ratings support comparisons under standardized test conditions. Your result depends on driving, weather, tyres, load, charging pattern and vehicle condition. The cost calculator uses the listed combined rating and your entered prices.